Greenville's only Boutique hotel, Hotel 27 is owned and operated by Main Street Greenville.

Hotel 27 is the only hotel currently owned and operated by a non-profit Organization in mississippi. Net proceeds from your stay at Hotel 27 help provide Grants and Technical Assistance to small businesses, support local students and schools, and drive downtown's economic development and revitalization efforts. 


For reservations, please visit www.Hotel27.org
211 S. Walnut Street
Greenville, MS 38701
​662-702-3681

Office Location

Main Street Greenville
504 Central Street
Greenville, MS 38701
Phone: 662-378-3121
Fax:      662-378-3966
[email protected]

About Our Organization

Main Street Greenville is a subsidiary of The Greater Greenville Development Foundation, Inc. which was developed exclusively for charitable, educational, scientific, and literary purposes. The purpose of the organization is to promote events and issues which are relevant to the quality of life for the residents of Greenville, Washington County, the Mississippi Delta and the State of Mississippi, including but not limited to, economic planning and development, education, housing and cultural development. 

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